Usage Note
Santidad can refer to moral or spiritual holiness in general, but its most recognized use in Spanish is as the honorific title for the Pope: Su Santidad (His Holiness). Do not confuse with sagrado (sacred, adjective) or santuario (sanctuary). The adjective form is santo/santa.
Examples
"Su Santidad presidió la ceremonia en Roma."
Natural Translation
His Holiness presided over the ceremony in Rome.

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