Usage Note
Personalmente either signals that the speaker is giving a personal opinion (personalmente, prefiero el café) or that something is done in person rather than by proxy (firmó personalmente el documento). This ambiguity usually resolves from context. In formal speech, en persona is a common synonym for the 'in person' sense.
Examples
"Personalmente, prefiero el té al café."
Natural Translation
Personally, I prefer tea to coffee.

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